Epigenetic regulations
| Nature | Unknown label |
|---|
| Credit hour | 3 |
|---|---|
| Total number of hours | 29 |
| Number of hours for lectures | 15 |
| Number of hours for tutorials | 7 |
| Number of hours for laboratory work | 7 |
Prerequisites
Basics of molecular biology and genetics
Goals
NC
Content
Lectures (CM): 15hrs
• General introduction about epigenetics
• DNA methylation, RNA directed DNA methylation and regulation of transposable elements
• Histone variants and their chaperones
• Histone code and chromatin states
• The amaizing small RNA world
• Nuclear architecture and 3D genome organization
• Epigenomics and Breeding applications
• Comparative epigenomics in plants
Round table discussion (TD) 7.5hrs
Analysis of scientific publications
• DNA methylation, RNA directed DNA methylation and regulation of transposable elements
• Histone variants and their chaperones
• Histone code and chromatin states
• The amaizing small RNA world
• Nuclear architecture and 3D genome organization
Practical course (TP): 7.5hrs (to be discussed, can be converted into publication analysis)
• Analysis of DNA methylation in plant by Bisulfite-Seq (BS-Seq) and/or ChiP-Seq analysis. An example of dataset linked to one publication analysed with the students.
• General introduction about epigenetics
• DNA methylation, RNA directed DNA methylation and regulation of transposable elements
• Histone variants and their chaperones
• Histone code and chromatin states
• The amaizing small RNA world
• Nuclear architecture and 3D genome organization
• Epigenomics and Breeding applications
• Comparative epigenomics in plants
Round table discussion (TD) 7.5hrs
Analysis of scientific publications
• DNA methylation, RNA directed DNA methylation and regulation of transposable elements
• Histone variants and their chaperones
• Histone code and chromatin states
• The amaizing small RNA world
• Nuclear architecture and 3D genome organization
Practical course (TP): 7.5hrs (to be discussed, can be converted into publication analysis)
• Analysis of DNA methylation in plant by Bisulfite-Seq (BS-Seq) and/or ChiP-Seq analysis. An example of dataset linked to one publication analysed with the students.
Additional Information
NC